Molecular and cellular biology of rhabdomyosarcoma

作者:De Giovanni Carla; Landuzzi Lorena; Nicoletti Giordano; Lollini Pier Luigi*; Nanni Patrizia
来源:Future Oncology, 2009, 5(9): 1449-1475.
DOI:10.2217/fon.09.97

摘要

Rhabdomyosarcoma is a group of soft-tissue sarcomas that share features of skeletal myogenesis, but show extensive heterogeneity in histology, age and site of onset, and prognosis, This review matches recent molecular data with biological features of rhabdomyosarcoma. Alterations in molecular pathways, animal models, cell of origin and potential new therapeutic targets are discussed.

  • 出版日期2009-11