Multiple Colon Ulcers with Typical Small Intestinal Lesions Induced by Non-Steroidal Anti-Inflammatory Drugs

作者：Akashi Momoko; Ando Takayuki; Hamashima Takeru; Yoshita Hiroki; Nanjo Sohachi; Mihara Hiroshi; Fujinami Haruka; Kajiura Shinya; Nishikawa Jun; Miura Yoshiaki; Hosokawa Ayumu; Sugiyama Toshiro^*

来源：Internal Medicine, 2015, 54(16): 1995-1999.

DOI：10.2169/internalmedicine.54.3919

• NSAID-induced ulcer
• total colon
• colonoscopy
• capsule endoscopy

The diagnosis of NSAID-induced colon ulcers is difficult when the distribution or endoscopic findings are not typical. An 83-year-old woman was transferred to our hospital for hemorrhagic diarrhea. Colonoscopy showed multiple ulcers in the entire colon, particularly longitudinal ulcers in the transverse colon. These were unusual for NSAID-induced colopathy, although she had been on meloxicam. However, capsule endoscopy revealed multiple scars and erosions, characteristic of NSAIDs users. The final diagnosis was NSAID-induced enteropathy, and all lesions were in remission after meloxicam discontinuation. We herein emphasize the value of an endoscopic assessment of the entire digestive tract in the diagnosis of NSAID-induced mucosal lesions.

• 出版日期2015