Analysis of Plasma Protein Concentrations and Enzyme Activities in Cattle within the Ex-Evacuation Zone of the Fukushima Daiichi Nuclear Plant Accident

作者：Urushihara Yusuke; Kawasumi Koh; Endo Satoru; Tanaka Kenichi; Hirakawa Yasuko; Hayashi Gohei; Sekine Tsutomu; Kino Yasushi; Kuwahara Yoshikazu; Suzuki Masatoshi; Fukumoto Motoi; Yamashiro Hideaki; Abe Yasuyuki; Fukuda Tomokazu; Shinoda Hisashi; Isogai Emiko; Arai Toshiro; Fukumoto Manabu

来源：PLos One, 2016, 11(5): e0155069.

DOI：10.1371/journal.pone.0155069

The effect of the Fukushima Daiichi Nuclear Power Plant (FNPP) accident on humans and the environment is a global concern. We performed biochemical analyses of plasma from 49 Japanese Black cattle that were euthanized in the ex-evacuation zone set within a 20-km radius of FNPP. Among radionuclides attributable to the FNPP accident, germanium gamma-ray spectrometry detected photopeaks only from Cs-134 and Cs-137 (radiocesium) commonly in the organs and in soil examined. Radioactivity concentration of radiocesium was the highest in skeletal muscles. Assuming that the animal body was composed of only skeletal muscles, the median of internal dose rate from radiocesium was 12.5 mu Gy/day (ranging from 1.6 to 33.9 mu Gy/day). The median of external dose rate calculating from the place the cattle were caught was 18.8 mu Gy/day (6.0-133.4 mu Gy/day). The median of internal and external (total) dose rate of the individual cattle was 26.9 mu Gy/day (9.11-55.1 mu Gy/day). Plasma levels of malondialdehyde and superoxide dismutase activity were positively and glutathione peroxidase activity was negatively correlated with internal dose rate. Plasma alanine transaminase activity and percent activity of lactate dehydrogenase (LDH)-2, LDH-3 and LDH-4 were positively and LDH-1 was negatively correlated with both internal and total dose rate. These suggest that chronic exposure to low-dose rate of ionizing radiation induces slight stress resulting in modified plasma protein and enzyme levels.

• 出版日期2016-5-9