Pulmonary inflammatory pseudotumor due to Coxiella burnetii. Case report and literature review

作者:Polo M F*; Mastrandrea S; Santoru L; Arcadu A; Masala G; Marras V; Bagella G; Sechi M M; Tanda F; Pirina P
来源:Microbes and Infection, 2015, 17(11-12): 795-798.
DOI:10.1016/j.micinf.2015.08.008

摘要

A 58-year-old man was admitted because of respiratory failure, episodic fever with chilling, cough, malaise, fatigue, myalgia and weight loss lasting for at least one month. Chest x-rays and CT scan of the chest showed bilateral pulmonary consolidations in upper lobes, the left lower lobe, and mediastinal lymphadenopathy. Bronchoscopy with cytology was unremarkable. A needle CT-guided lung biopsy documented an inflammatory pseudotumor, lymphoplasmacytic type. Serology showed high titer antibodies to phase II Coxiella burnetii infection. Therapy with doxycycline and hydroxychloroquine for three months led to a complete resolution of symptoms and radiological findings, and a marked decrease in titers to Q fever.

  • 出版日期2015-12