Atypical metastatic carcinoid of the uterine cervix and review of the literature

作者：Yoshida Yoshio^*; Sato Kumiko; Katayama Kanji; Yamaguchi Akio; Imamura Yoshiaki; Kotsuji Fumikazu

来源：Journal of Obstetrics and Gynaecology Research, 2011, 37(6): 636-640.

DOI：10.1111/j.1447-0756.2010.01402.x

• atypical carcinoid tumor
• hepatic arterial chemoembolization
• liver metastases
• neuroendocrine tumors

Atypical carcinoid tumors of the uterine cervix represent rare neuroendocrine tumors and are highly aggressive, showing early lymphatic invasion and hematogenous distant metastases. Because of the small number of cases, there are currently no recommendations regarding treatment, and little is known about the response to chemotherapeutic agents. A 39-year-old woman was diagnosed with a primary atypical carcinoid of the uterine cervix with numerous metastases to the liver. After radical hysterectomy, she underwent hepatic arterial chemoembolization with streptozotocin and 5-fluorouracil. Complete response was achieved in numerous liver metastases. At the 2-year follow up of chemotherapy, the patient remains alive. Treatment for atypical carcinoid tumors remains elusive, however hepatic arterial chemoembolization with streptozotocin and 5-fluorouracil was effective in the present primary atypical carcinoid with liver metastases. A review of the previous reports is also presented.

• 出版日期2011-6