A single-step one pot synthesis of O,O%26apos;-dialkyl N,N-dialkylphosphoramidates from dialkylphosphites

作者：Purohit Ajay Kumar; Pardasani Deepak; Kumar Ajeet; Goud D Raghavender; Jain Rajiv; Dubey D K

来源：Tetrahedron Letters, 2016, 57(33): 3754-3756.

DOI：10.1016/j.tetlet.2016.07.019

• Chemical warfare agent
• Chemical weapons convention
• Tabun
• Dialkylphosphite
• Phosphoramidates

An efficient synthetic method has been developed to obtain chemical weapons convention (CWC)-related O,O'-dialkyl-N,N-dialkylphosphoramidates from dialkylphosphites using inorganic reagents (CuCl2 and Cs2CO3) at room temperature.