Age-Related Features of Cytoflavin Effectiveness During Experimental Myocardial Ischemia

作者:Zhernakova N I; Gorbach T V; Romashchenko O V*; Rumbesht V V
来源:Bulletin of Experimental Biology and Medicine, 2014, 156(6): 785-788.
DOI:10.1007/s10517-014-2450-z

摘要

Administration of Cytoflavin to young rats with experimental myocardial ischemia was followed by activation of mitochondrial enzymes and significant accumulation of ATP in the myocardium and blood plasma, but did not modulate the stability of cardiomyocyte membranes and signs of hypoxia. Cytoflavin increased the severity of metabolic disorders and depleted the energy reserves of cells in old rats with myocardial ischemia.

  • 出版日期2014-4

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