A Patient With Henoch-Schonlein Purpura Manifesting Unusual Symptoms and Clinical Course

作者：Miyazawa Tomoki; Sugimoto Keisuke; Fujita Shinsuke; Miyazaki Kohei; Takemura Yutaka; Yanagida Hidehiko; Sakata Naoki; Wada Norihisa; Okada Mitsuru; Takemura Tsukasa^*

来源：Journal of Clinical Rheumatology, 2010, 16(7): 338-340.

DOI：10.1097/RHU.0b013e3181f4de99

• Henoch-Schonlein purpura
• neurologic presentation
• convulsions
• vasculitis
• limb pain
• factor XIII
• atypical course

We evaluated and treated a girl with Henoch-Schonlein purpura (HSP), who initially developed redness, swelling, and pain in all 4 limbs accompanied by Raynaud syndrome and then had convulsions and disturbance of consciousness. HSP was diagnosed based on later findings of purpura in both legs and a decrease in factor XIII activity not accompanied by thrombocytopenia. She was normotensive. A skin biopsy specimen showed small-vessel vasculitis accompanied by immunoglobulin A deposition. The cause of erythema and limb pain, convulsions, and disturbed consciousness presumably was vasculitis. The possibility of HSP should be considered in patients with limb pain despite initial absence of purpura and in patients with central nervous system symptoms such as convulsions.

• 出版日期2010-10