A Cooperative Catalytic System of Platinum/Iridium Alloyed Nanoclusters and a Dimeric Catechol Derivative: An Efficient Synthesis of Quinazolines Through a Sequential Aerobic Oxidative Process

作者：Yuan Hao; Yoo Woo Jin; Miyamura Hiroyuki; Kobayashi Shu^*

来源：Advanced Synthesis & Catalysis, 2012, 354(16): 2899-2904.

DOI：10.1002/adsc.201200880

• aerobic oxidation
• cooperative catalysis
• nanoclusters
• platinum/iridium alloy
• quinazolines

A cooperative catalytic system of heterogeneous polymer-supported bi-metallic platinum/iridium (Pt/Ir) alloyed nanoclusters and 5,5',6,6'-tetrahydroxy-3,3,3',3'-tetramethyl-1,1'-spiro-bisindane (TTSBI) enabled the facile preparation of quinazoline derivatives with low catalyst loadings and broad substrate scope under mild aerobic oxidative conditions. The ability to perform the reaction in gram-scale and under open-air conditions highlights the synthetic application of this cooperative catalytic system.

• 出版日期2012-11