Divergent synthesis of functionalized thioethers via multicomponent reaction of benzynes

作者:Jian, Hui; Wang, Qiang; Wang, Wei-Hua; Li, Zhi-Juan; Gu, Cheng-Zhi; Dai, Bin; He, Lin*
来源:Tetrahedron, 2018, 74(23): 2876-2883.
DOI:10.1016/j.tet.2018.04.072

摘要

Diverse functionalized thioethers were efficiently synthesized through the multicomponent reaction of benzynes, cyclic thioethers and different nucleophiles. Both inorganic salts (KF, KC1, KBr, and KSCN) and silylated reagents (TMSCN, TMSN3, TMSCI can be utilized as efficient nucleophiles for the reaction.