Diagnostic utility of enzyme-linked immunospot assay for interferon-gamma in a patient with tuberculous arthritis and pyomyositis

作者：Tan Che Kim; Lai Chih Cheng; Lin Sheng Hsiang; Huang Yu Tsung; Liao Chun Hsing; Hsueh Po Ren^*

来源：Journal of Microbiology, Immunology, and Infection, 2011, 44(5): 397-400.

DOI：10.1016/j.jmii.2010.03.003

• Enzyme-linked immunospot assay
• Interferon-gamma
• Mycobacterium tuberculosis
• Tuberculous arthritis
• Tuberculous pyomyositis

The indolent and nonspecific presentations of tuberculous arthritis and pyomyositis render their diagnosis a great challenge for clinicians. We describe a 78-year-old man with swelling and pain of right knee for 6 months. The patient was empirically treated for tuberculosis because positive enzyme-linked immunospot assay for interferon-gamma of blood was reported at 2 days after aspiration of synovial fluid, which was negative for acid-fast stain but subsequently grew Mycobacterium tuberculosis 6 weeks later. He recovered uneventfully with 1-year antituberculous combination therapy.

• 出版日期2011-10