A New Phosphotungstic Acid Salt, [Et3NH](3)PW12O40: Synthesis, Characterization and Its Application as Catalyst in the Synthesis of 4(3H)-Quinazolinones

作者：Tavakoli Hoseini Niloofar^*; Davoodnia Abolghasem

来源：Synthesis and Reactivity in Inorganic Metal-Organic and Nano-Metal Chemistry, 2012, 42(1): 76-81.

DOI：10.1080/15533174.2011.609232

• 4(3H)-quinazolinones
• organic heteropolyacid salt
• solid acid
• triethylamine
• 12-phosphotungstic acid

A new Bronsted acidic ionic salt based on Keggin phosphotungstate anion, [Et3NH](3)PW12O40, has been synthesized using 12-phosphotungstic acid, H3PW12O40, and triethylamine. The salt has an ionic liquid-like composition but possesses a high melting point. It was characterized by H-1 NMR, C-13 NMR, FT-IR, and CHN analysis, and catalytically evaluated in the synthesis of 4(3H)-quinazolinones by cyclocondensation of 2-aminobenzamide with aroyl chlorides. It showed high catalytic activity with good to excellent yields of the desired products. Furthermore, the products could be separated simply from the catalyst, and the catalyst could be recycled and reused without substantial reduction in its catalytic activity.

• 出版日期2012