A Novel Coordinated Polymer [Cu(En)(2)][(PzTp)Fe(CN)(3)](2): Synthesis, Crystal Structure, and Inhibiting Left Atrial Myxoma Cell Activity in vitro

作者：Zhou, X. L.; Dong, F. Q.; Hong, C. L.; Chen, D. K.; He, F.^*

来源：Russian Journal of Coordination Chemistry, 2018, 44(3): 179-182.

DOI：10.1134/S1070328418030089

• cyanide-bridged
• X-ray
• anticancer activity

A new cyanide-bridged neutral centrosymmetric cluster [Cu(En)(2)][(PzTp)Fe(CN)(3)](2) (I), where En = ethylenediamine, PzTp = tetra(pyrazol-1-yl)borate) was synthesized by a programmed self-assembly of preformed building blocks. Characterization with single crystal X-ray diffraction (CIF file CCDC no. 1555334) showed that the Cu2+ center was located in a large distorted octahedral environment due to the obvious Jahn-Teller effect, which was demonstrated by continuous shape measures with the SHAPE program. Furthermore, no coordinated or free solvent molecules existed in the clusters, showing good roomtemperature stability. In addition, in vitro anticancer activity of compound I on three human cancer cells (SKOV3, A2780, and OVCAR) was further determined.

• 出版日期2018-3
• 单位深圳大学; 温州医科大学