Dry and wet prolines for asymmetric organic solvent-free aldehyde-aldehyde and aldehyde-ketone aldol reactions

作者:Hayashi Yujiro*; Aratake Seiji; Itoh Takahiko; Okano Tsubasa; Sumiya Tatsunobu; Shoji Mitsuru
来源:Chemical communications, 2007, (9): 957-959.
DOI:10.1039/b613262f

摘要

Dry and wet prolines were found to catalyze the direct aldol reactions of aldehyde-aldehyde and aldehyde-ketone, respectively, to afford aldols with excellent diastereo- and enantio-selectivities, and an organic solvent-free reaction was realized in some cases.

  • 出版日期2007-3-7