摘要

An atom-efficient, one-pot, three-component synthetic methodology has been developed for the preparation of alpha-aminophosphonates using the crystalline CuO- nanopowder as catalyst in solvent-free and ambient conditions, for the first time. The reaction involves the use of carbonyl compounds, amines and trimethyl phosphite. A wide range of substrates is compatible in this reaction, producing excellent yields in short time. The catalyst is recyclable with reproducible results.

  • 出版日期2011