Use of hepatobiliary phase images in Gd-EOB-DTPA-enhanced MRI of breast cancer hepatic metastasis to predict response to chemotherapy

作者：Lee Hyun Ji; Lee Chang Hee^*; Kim Jeong Woo; Park Yang Shin; Lee Jongmee; Kim Kyeong Ah

来源：Clinical Imaging, 2017, 43: 127-131.

DOI：10.1016/j.clinimag.2017.03.005

• Gadoxetic acid
• MRI
• Hepatobiliary phase (HBP)
• Breast cancer liver metastases
• Chemotherapy response

Objectives: To determine the prognostic value of Gd-EOB-DTPA MRI findings of liver metastasis from breast cancer.
Methods: 29 metastatic lesions from 12 breast cancer patients who received chemotherapy were retrospectively reviewed. We evaluated hepatobiliary phase of the lesions and classified them as a "target" or "non-target" appearance. The relationship of appearance or SI ratio with tumor response was analyzed.
Results: A non-target appearance was more frequent in disease control group than in non-control group [14/18 (77.8%) vs. 4/18 (222%)], and it was associated with a better response [p = 0.048].
Conclusion: HBP analysis may be useful to predict the response to chemotherapy and survival.

• 出版日期2017-6