Anemia is Associated With Mortality Following Endovascular Repair of Abdominal Aortic Aneurysm

作者：Saratzis Athanasios^*; Melas Nikolaos; Hunter James P; Dixon Hannah; Nightingale Peter; Kiskinis Dimitrios; Saratzis Nikolaos; Kitas George D

来源：Vascular and Endovascular Surgery, 2012, 46(3): 223-228.

DOI：10.1177/1538574412442251

• abdominal aortic aneurysm
• endovascular
• anemia
• outcome

Aim: The aim of this study was to compare midterm mortality between anemic and nonanemic patients undergoing endovascular repair of abdominal aortic aneurysm and to assess a correlation with markers of inflammation. Methods: Anemia was defined as hemoglobin %26lt; 13 (men) and %26lt; 12 g/dL (women). The impact of anemia and inflammatory markers on mortality was assessed using Kaplan-Meier curves and Cox regression. Results: A total of 224 patients (12 females [5.36%]; age: 69.73 +/- 8.72 years) were included; 102 (45.53%) were anemic. Median follow-up was 17 months (interquartile range: 7-25 months). Nine patients died (1.79%; 8 anemic vs 1 nonanemic). Survival was lower for patients with anemia (log-rank, P = .01). White blood cell count and C-reactive protein (CRP) differed significantly (P %26lt; .001 and P = .01). Anemia and CRP were associated with decreased survival (Cox regression, P = .01, hazard ratio [HR]: 0.35, 95% confidence interval: 0.14-0.84 and P = .002, HR: 1.18, 95% CI: 1.06-1.31). Conclusion: Patients with anemia had decreased survival over the midterm; inflammatory markers were higher among this group.

• 出版日期2012-4