Decision aids for localized prostate cancer treatment choice: Systematic review and meta-analysis

作者:Violette Philippe D; Agoritsas Thomas; Alexander Paul; Riikonen Jarno; Santti Henrikki; Agarwal Arnav; Bhatnagar Neera; Dahm Philipp; Montori Victor; Guyatt Gordon H; Tikkinen Kari A O*
来源:CA: A Cancer Journal for Clinicians , 2015, 65(3): 239-251.
DOI:10.3322/caac.21272

摘要

Patients who are diagnosed with localized prostate cancer need to make critical treatment decisions that are sensitive to their values and preferences. The role of decision aids in facilitating these decisions is unknown. The authors conducted a systematic review of randomized trials of decision aids for localized prostate cancer. Teams of 2 reviewers independently identified, selected, and abstracted data from 14 eligible trials (n=3377 men), of which 10 were conducted in North America. Of these, 11 trials compared decision aids with usual care, and 3 trials compared decision aids with other decision aids. Two trials suggested a modest positive impact on decisional regret. Results across studies varied widely for decisional conflict (4 studies), satisfaction with decision (2 studies), and knowledge (2 studies). No impact on treatment choices was observed (6 studies). In conclusion, scant evidence at high risk of bias suggests the variable impact of existing decision aids on a limited set of decisional processes and outcomes. Because current decision aids provide information but do not directly facilitate shared decision making, subsequent efforts would benefit from user-centered design of decision aids that promote shared decision making. CA Cancer J Clin 2015;65: 239-251.

  • 出版日期2015-6