A new and potentially prebiotic alpha-cytidine derivative

作者:Tsanakopoulou Maria; Xu Jianfeng; Bond Andrew D; Sutherland John D*
来源:Chemical Communications, 2017, 53(23): 3327-3329.
DOI:10.1039/c7cc00693d

摘要

A new alpha-cytidine derivative was synthesised from the prebiotic reaction of ribose aminooxazoline and dicyanoacetylene. The tetracyclic structure of the product was confirmed by X-ray diffraction and then an alternative 6-step synthetic pathway to the product was found which was suitable for large-scale synthesis.

  • 出版日期2017-3-21