科研之友
微信
新浪微博
Facebook
分享链接
摘要
Enantiomerically enriched fluorinated benzo-fused bicyclic homoallylic amities have been synthesized through an asymmetric allylation/ring closing metathesis (RCM) sequence. This sequence has been carried out using alpha-trifluoromethylstyrene derivatives as key intermediates, synthesized by microwave radiation. The great deactivating effect exerted by such substituents has been brought to light by a comparative study.
- 出版日期2016-10-7
