Uniform polymer particles formulated with ultraviolet protective materials for the protection of UV sensitive molecules

作者：Steeley Kristin G; Kuestermeyer Brett; Stanton Chelsea; Yu Joel; Morabito Kenneth; Li Dapeng; Mello Charlene; Calvert Paul; Tripathi Anubhav; Shapley Nina C^*

来源：Dyes and Pigments, 2014, 105: 12-22.

DOI：10.1016/j.dyepig.2013.12.013

• Photostability
• Beta-carotene
• Solvent-evaporation technique
• Suspensions

Ultraviolet radiation can cause significant degradation of skin, pharmaceuticals, and other materials. Previous work has shown that encapsulation of ultraviolet sensitive molecules or proximity to protective molecules can provide protection from photo-oxidation. This study explores the protective capacity of uniform polymeric particles containing both ultraviolet sensitive materials (beta-carotene) and ultraviolet protective materials (ultraviolet absorbers oxybenzone, avobenzone, and octyl-4-methoxycinnamate and the antioxidant vitamin E). Oxybenzone and avobenzone provided the most protection when used singly and provided the best protection overall when paired with vitamin E, preserving over 80% of the beta-carotene after 60 min of exposure. Ultraviolet absorber combinations did not show a synergistic effect due to photosensitization.

• 出版日期2014-6
• 单位rutgers