Multiple ST clonal complexes, with a predominance of ST131, of Escherichia coli harbouring bla(CTX-M-15) in a tertiary hospital in Tanzania

作者：Mshana S E; Imirzalioglu C^*; Hain T; Domann E; Lyamuya E F; Chakraborty T

来源：Clinical Microbiology and Infection, 2011, 17(8): 1279-1282.

DOI：10.1111/j.1469-0691.2011.03518.x

• bla(CTX-M-15)
• Escherichia coli
• ST131
• Tanzania

The molecular epidemiology of 32 non-duplicate, CTX-M-15 extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli strains, isolated from clinical samples, was investigated. Multilocus sequence typing revealed multiple sequence type clonal complexes: ST131 (12), ST405 (4), ST638 (3), ST38 (2), ST827 (2), ST224 (1), ST648 (1), ST46 (1) and two new sequence type clonal complexes (1845 and 1848) in 22 pulsed field gel electrophoresis clusters. The bla(CTX-M-15) gene was located on conjugative IncF plasmids. This is the first report of the worldwide emerging clonal complex ST131 linked to bla(CTX-M-15) in Tanzania and demonstrates the need for constant surveillance in developing countries to prevent the spread of these multiresistant isolates.

• 出版日期2011-8
• 单位河北医科大学