An ultrasensitive electrochemical impedance sensor for a special BRCA1 breast cancer gene sequence based on lambda exonuclease assisted target recycling amplification

作者:Xu, Huifeng; Wang, Lili; Ye, Hongzhi; Yu, Lishuang; Zhu, Xi; Lin, Zhenyu; Wu, Guangwen; Li, Xihai; Liu, Xianxiang*; Chen, Guonan
来源:Chemical communications, 2012, 48(51): 6390-6392.
DOI:10.1039/c2cc31588b

摘要

A label-free, target recycling electrochemical impedance spectroscopy (EIS) DNA sensor has been developed for detection of a model related to the BRCA1 breast cancer gene with a detection limit of 0.05 nM.