科研之友
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摘要
New 5-nitroindazole derivatives substituted in 1st position with radicals that contains the di-(beta-chloroethyl)-amine group have been synthesized in order to obtain substances with enhanced antitumor activity. The structure of the new compounds has been confirmed by elemental and spectral analyses (H-1-NMR and FT-IR). The potential cytostatic action of the compounds studied on Guerin experimental tumors proves that new alkylating agents significantly suppress the proliferation of the neoplastic cells.
- 出版日期2012-3
