Iterative strategies for the synthesis of deoxypropionates

作者:ter Horst Bjorn; Feringa Ben L*; Minnaard Adriaan J
来源:Chemical Communications, 2010, 46(15): 2535-2547.
DOI:10.1039/b926265b

摘要

This feature article gives an overview of iterative synthetic methods for the construction of deoxypropionates, an important class of polyketides. The catalytic and non-catalytic methodologies discussed are based on highly stereoselective reactions which can be carried out in an iterative fashion. Non-catalytic methods are described first, followed by state of the art catalytic iterative protocols. The application of the iterative methods in the synthesis of natural products is discussed as well.

  • 出版日期2010