Schinarisanlactone A, a New Bisnortriterpenoid from Schisandra arisanensis

作者：Lin Yu Chi; Lo I Wen; Chen Shun Ying; Lin Pi Han; Chien Ching Te; Chang Sui yuan; Shen Ya Ching^*

来源：Organic Letters, 2011, 13(3): 446-449.

DOI：10.1021/ol102772j

A novel triterpenold, schinarisanlactone A (1), was isolated from the fruits of Schisandra arisanensis. Compound 1 possesses an unprecedented skeleton having a 5/7/7/5/7/5/6/5-fused octacyclic ring system. The structure of 1 was determined by 2D NMR techniques (COSY, HMQC, HMBC, and NOESY) and was confirmed by X-ray crystallographic analysis. Schinarisanlactone A (1) exhibited significant anti-HIV activity.

• 出版日期2011-2-4