摘要

For decades NSAIDs are being used in the treatment of primary headache disorders with great benefit for patients. They belong to the basic treatment options for migraine as well as tension type headache. For the use of NSAIDs in the treatment of the remaining primary headaches there are data existing that support a differentiated use. Despite the knowledge of the effects of NSAIDs on cyclooxygenase 1 and 2 not all of the mechanisms of interaction with processes in headache relevant pathophysiology are understood. Here we present an overview of the newest research on NSAIDs relevant to headaches, the current guidelines for the treatment of primary headaches and their mentioning of NSAIDs, the known mechanisms of action as well as the most important side effects.

  • 出版日期2013