Antioxidant Flavone Glycosides from the Root of Pteroxygonum giraldii

作者:Li Bao Lin*; Yang Zhan Jun; Jiang Lin Ling; Zhang Xi Quan; Gu Hong Mei; Wang Hui Chun; Tian Xian Hua
来源:Bulletin of the Korean Chemical Society, 2009, 30(7): 1459-1462.
DOI:10.5012/bkcs.2009.30.7.1459

摘要

Two new flavone glycosides, giraldiin A and B, together with three known compounds, annulatin, myricetin 3-O-alpha-L-rhamnopyranoside and gallic acid, were isolated from the ethanol extract of the root of Pteroxygonum giraldii Damm. et Diels. The Structures of giraldiin A and B are designated as 3'-(alpha-L-arabinopyranosyloxy)-4',5,5',7-tetrahydroxy-3-methoxyflavone and 4'-(beta-D-glucopyranosyloxy)-5,5',7-trihydroxy-2',3-dimethoxyflavone, respectively, oil the basis of detailed spectroscopic analyses. The free radical scavenging activity of giraldiin A was evaluated by decolouring spectrophotometry of pentamethine cyanine dye (Cy5) with Fe(2+)-H(2)O(2) Fenton radical generating system. The results indicated the hydroxyl free radical scavenging activity of giraldiin A (ED(50) = 23.7 nmol/mL) is higher than that of some known antioxidants such as rutin, puerarin, daidzein and 2,6-di-tert-buyl-4-methyl phenol.