Ni-0-catalyzed Direct Amination of Anisoles Involving the Cleavage of Carbon-Oxygen Bonds

作者:Tobisu Mamoru*; Shimasaki Toshiaki; Chatani Naoto
来源:Chemistry Letters, 2009, 38(7): 710-711.
DOI:10.1246/cl.2009.710

摘要

Ni-0-catalyzed cross-coupling of aryl methyl ethers with amines is described. The use of an N-heterocyclic carbene as a ligand and NaOt-Bu as a base promotes the amination of anisole derivatives via the cleavage of normally unreactive aryl carbon-oxygen bonds.

  • 出版日期2009-7-5