Umbilical metastasis: a case series of four Sister Joseph nodules from four different visceral malignancies

作者：Palaniappan M^*; Jose W M; Mehta A; Kumar K; Pavithran K

来源：Current Oncology, 2010, 17(6): 78-81.

DOI：10.3747/co.v17i6.684

• Sister Mary Joseph
• umbilical nodule
• gallbladder carcinoma
• malignant gist
• ovarian carcinoma
• rectal carcinoma

Sister Joseph nodule is a metastatic umbilical lesion secondary to a primary malignancy of any viscera. It can be a presenting symptom (a sign of undiagnosed malignancy) or a symptom or sign of progression or recurrence in a known case. Its incidence is 1%-3% of all intra-abdominal or pelvic malignancies. Here, we present 4 such cases, with Sister Joseph nodule as a finding of
presentation in a case of gallbladder carcinoma,
progression in a case of malignant gastrointestinal stromal tumour,
recurrence in a case of ovarian carcinoma, and
presentation in a case of rectal carcinoma.
The clinicopathologic features of all 4 patients are discussed, and the related literature is briefly reviewed.

• 出版日期2010
• 单位河北医科大学