A Polypyrrole-Imprinted Electrochemical Sensor Based on Nano-SnO2/Multiwalled Carbon Nanotubes Film Modified Carbon Electrode for the Determination of Oleanolic Acid

作者：Zhang, Zhaohui^*; Luo, Lijuan; Chen, Hongjun; Zhang, Minglei; Yang, Xiao; Yao, Shouzhuo; Li, Jiaxing; Peng, Mijun

来源：Electroanalysis, 2011, 23(10): 2446-2455.

DOI：10.1002/elan.201100231

• Molecularly imprinted polymer (MIP)
• Multiwalled carbon nanotubes (MWNTs)
• Tin oxide nanoparticles (nano-SnO2)
• Oleanolic acid

A sensitive molecularly imprinted electrochemical sensor with specific recognition ability for oleanolic acid was synthesized by modification of multiwalled carbon nanotubes (MWNTs) decorated with tin oxide nanoparticles (nano-SnO2/MWNTs) and polypyrrole-imprinted polymer on a carbon electrode. The morphology and electrochemical performance of the imprinted sensor were investigated by using scanning electron microscope (SEM), X-ray diffraction (XRD), cyclic voltammetry (CV), linear sweep voltammetry (LSV) and amperometric i-t curve. The results showed that the imprinted sensor displayed excellent selectivity toward oleanolic acid. A linear relationship between the response currents and oleanolic acid concentrations ranging from 5.0x10(-8) g/L to 2.0x10(-5) g/L was obtained for the imprinted sensor. The limit of detection (LOD) of the imprinted sensor toward oleanolic acid was calculated as 8.6x10(-9) g/L at a signal to noise ratio (SIN) of 3. This imprinted sensor was successfully applied to the determination of oleanolic acid in Acitinidia deliciosa root samples.

• 出版日期2011-10
• 单位湖南大学; 吉首大学