Advances in Statistical Approaches to Oncology Drug Development

作者：Ivanova Anastasia^*; Rosner Gary L; Marchenko Olga; Parke Tom; Perevozskaya Inna; Wang Yanping

来源：Therapeutic Innovation & Regulatory Science, 2014, 48(1): 81-89.

DOI：10.1177/2168479013501309

• cancer trial
• oncology drug development
• MTD
• model-based design
• stopping rule

The authors describe some recent developments in statistical methods and practice in oncology drug development from an academic and an industry perspective. Many adaptive designs were pioneered in oncology, and oncology is still at the forefront of novel methods to enable better and faster go/no-go decision making while controlling the cost.

• 出版日期2014-1