A simple and straightforward synthesis of substituted 2-arylbenzimidazoles over silica gel

作者:Chaturvedi Amit K*; Negi Arvind S; Khare Puja
来源:RSC Advances, 2013, 3(14): 4500-4504.
DOI:10.1039/c3ra22435j

摘要

A solid phase strategy for the synthesis of substituted 2-arylbenzimidazoles over silica gel has been achieved starting from their corresponding o-phenylenediamines 1 and aromatic aldehydes 2. The reaction is very simple, convenient and straightforward, and the products are obtained in moderate to high yields (49-91%).