Ultrasonic enhancing amorphization during synthesis of calcium phosphate

作者：He Kun; Xiao Gui Yong; Xu Wen Hua; Zhu Rui Fu; Lu Yu Peng^*

来源：Ultrasonics Sonochemistry, 2014, 21(2): 499-504.

DOI：10.1016/j.ultsonch.2013.08.011

• Amorphous calcium phosphate (ACP)
• Ultrasonic
• Crystallinity
• Hydroxyapatite

Amorphous calcium phosphate (ACP) has great application potential in biomaterials field due to its non-cytotoxicity, high bioactivity, good cytocompatibility, and so on. The results of this research demonstrated that ultrasonic obviously enhanced amorphization during synthesis of calcium phosphate. The ACP phase was relatively ideal when the solvent of Ca(NO3)(2)center dot 4H(2)O was ethanol and the solvent of (NH4)(2)HPO4 was a mixture of water and ethanol, under ultrasonic. In-situ crystallization of ACP could be observed by HRTEM. The mechanism on the effects of ultrasonic on amorphization of the synthesized calcium phosphate was discussed. It was suggested that ultrasonic synthesis might be a facile method to prepare pure and safe ACP related biomaterials.

• 出版日期2014-3
• 单位山东大学