A new 20-membered macrolide produced by a marine-derived Micromonospora strain

作者:Peng Fei; Wang Chuan-xi; Xie Yang; Jiang Hong-lei; Chen Lu-jie; Uribe, Paulina; Bull, Alan T.; Goodfellow, Michael; Jiang Hong; Lian Yun-yang*
来源:Natural Product Research, 2013, 27(15): 1366-1371.
DOI:10.1080/14786419.2012.740038

摘要

A new 20-membered macrolide named as levantilide C was isolated from the Micromonospora strain FIM07-0019 recovered from shallow coastal waters near the island of Chiloe, Chile. The chemical structure of levantilide C was elucidated on the basis of one- and two-dimensional NMR analysis. Two known indole derivatives were also isolated from this strain. Levantilide C exhibited moderate antiproliferative activity against several tumour cell lines.