Arousal modulates activity in the medial temporal lobe during a short-term relational memory task

作者：Thoresen Christian^*; Jensen Jimmy; Sigvartsen Niels Petter B; Bolstad Ingeborg; Server Andres; Nakstad Per H; Andreassen Olea A; Endestad Tor

来源：Frontiers in Human Neuroscience, 2012, 5: 177.

DOI：10.3389/fnhum.2011.00177

• amygdala
• arousal
• fMRI
• hippocampus
• relational memory
• serial position effect
• short-term memory

This study investigated the effect of arousal on short-term relational memory and its underlying cortical network. Seventeen healthy participants performed a picture by location, short-term relational memory task using emotional pictures. Functional magnetic resonance imaging was used to measure the blood-oxygenation-level dependent signal relative to task. Subjects' own ratings of the pictures were used to obtain subjective arousal ratings. Subjective arousal was found to have a dose-dependent effect on activations in the prefrontal cortex, amygdala, hippocampus, and in higher order visual areas. Serial position analyses showed that high arousal trials produced a stronger primacy and recency effect than low arousal trials. The results indicate that short-term relational memory may be facilitated by arousal and that this may be modulated by a dose-response function in arousal driven neuronal regions.

• 出版日期2012-1-3