EBV-positive large B-cell lymphomas in young patients: a nodal lymphoma with evidence for a tolerogenic immune environment

作者：Nicolae Alina; Pittaluga Stefania; Abdullah Shahed; Steinberg Seth M; Thu Anh Pham; Davies Hill Theresa; Xi Liqiang; Raffeld Mark; Jaffe Elaine S

来源：Blood, 2015, 126(7): 863-872.

DOI：10.1182/blood-2015-02-630632

<jats:title>Key Points</jats:title>
<jats:p>EBV+ LBCLs in young patients resemble those seen in the elderly, but usually have a good outcome. Tumor cells exhibit PD-L1 expression, with high indoleamine 2,3-dioxygenase–positive cell content, indications of a tolerogenic immune state.</jats:p>

• 出版日期2015-8-13