Nanofibrous Lipid Membranes Capable of Functionally Immobilizing Antibodies and Capturing Specific Cells

作者:Zha Zhengbao; Cohn Celine; Dai Zhifei*; Qiu Weiguo; Zhang Jinhong; Wu Xiaoyi
来源:Advanced Materials, 2011, 23(30): 3435-+.
DOI:10.1002/adma.201101516

摘要

Polymerizable cholesteryl-succinyl silane was synthesized and fabricated into stable nanofibrous lipid membranes using a combined sol-gel and electrospinning process. The resulting nanofibrous lipid membranes are capable of functionally immobilizing membrane proteins such as antibodies, thereby enabling targeted cell capture via the antigen-antibody interactions.