Drug-Induced Glomerular Disease: Immune-Mediated Injury

作者:Hogan Jonathan J*; Markowitz Glen S; Radhakrishnan Jai
来源:Clinical Journal of the American Society of Nephrology, 2015, 10(7): 1300-1310.
DOI:10.2215/CJN.01910215

摘要

Drug-induced autoimmune disease was initially described decades ago, with reports of vasculitis and a lupus-like syndrome in patients taking hydralazine, procainamide, and sulfadiazine. Over the years, multiple other agents have been linked to immune-mediated glomerular disease, often with associated autoantibody formation. Certain clinical and laboratory features may distinguish these entities from their idiopathic counterparts, and making this distinction is important in the diagnosis and management of these patients. Here, drug-induced, ANCA-associated vasculitis, drug-induced lupus, and drug-associated membranous nephropathy are reviewed.

  • 出版日期2015-7