Histone Deacetylase Inhibitors in Cancer: What Have We Learned?

作者:Whittle James R; Desai Jayesh*
来源:Cancer, 2015, 121(8): 1164-1167.
DOI:10.1002/cncr.29177

摘要

The authors outline the current stage in the development of histone deacetylase inhibitors in solid tumors. Despite single-agent benefit in a small number of hematologic malignancies, evidence in solid organ cancers suggests that outcomes will be more promising with combination therapy and should be the focus of future studies.

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