Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss

作者:Ramos Paulo Muller*; Brianezi Gabrielli; Pereira Martins Ana Carolina; da Silva Marcia Guimaraes; Alencar Marques Mariangela Esther; Miot Helio Amante
来源:Anais Brasileiros de Dermatologia, 2017, 92(3): 430-431.
DOI:10.1590/abd1806-4841.20175150

摘要

The etiopathogenesis of female pattern hair loss is still poorly understood. In addition to genetic and hormonal elements, environmental factors could be involved. The aryl hydrocarbon receptor is expressed in keratinocytes and can be activated by environmental pollutants leading to alterations in the cell cycle, inflammation, and apoptosis. Here we demonstrate the overexpression of nuclear aryl hydrocarbon receptors in miniaturized hair follicles in female pattern hair loss.

  • 出版日期2017-6