A heterogeneous copper(I)-catalyzed aerobic oxidative cross-dehydrogenative coupling of terminal allcynes with thiols leading to alkynyl sulfides

作者：Fang, Zhiqiang; He, Wen; Cai, Mingzhong^*; Lin, Yang; Zhao, Hong

来源：Tetrahedron Letters, 2015, 56(46): 6463-6467.

DOI：10.1016/j.tetlet.2015.09.153

• Copper
• Cross-dehydrogenative coupling
• Alkynyl sulfide
• MCM-41
• Heterogeneous catalysis

A heterogeneous copper-catalyzed direct oxidative cross-dehydrogenative coupling of terminal alkynes with thiols was achieved in DMSO at 70 degrees C in the presence of an MCM-41-supported bidentate nitrogen copper(I) complex [MCM-41-2N-CuCl] and K2CO3 under an atmosphere of O-2, yielding selectively a variety of alkynyl sulfides in good to excellent yields. This heterogeneous copper catalyst can be easily recovered by a simple filtration and recycled 10 times without any decreases in activity.

• 出版日期2015-11-18
• 单位江西师范大学; 广东药科大学