Nucleosome mapping in plasma DNA predicts cancer gene expression

作者:Murtaza Muhammed*; Caldas Carlos
来源:Nature Genetics, 2016, 48(10): 1105-1106.
DOI:10.1038/ng.3686

摘要

A new study demonstrates that genomic sequencing coverage of plasma DNA fragments around transcription start sites reflects the expression levels of genes in corresponding tumors. This approach may enable noninvasive monitoring of treatment-induced changes in gene expression for patients with cancer.

  • 出版日期2016-10