科研之友
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摘要
The hydration layers and subsequent secondary structures of adsorbed proteins on the hydroxyapatite (HA) hybridized with mesoporous silica (MS) particles (HA/MS) were investigated using an infrared spectral separation technique. The hydration structures on HA/MS were clearly different from those on the MS and HA alone, which would affect the protein absorption behaviors. In particular, HA/MS exhibited the higher protein adsorption amounts at the biological concentrations, and induced the steric conformation structures for albumin and suppressed the random structures for immunoglobulin G in the adsorption processes, suggesting the controllable interfacial layers by the hybridization of HA with MS.
- 出版日期2017-12-15
