Aggregation behaviour of gold nanoparticles in presence of chitosan

作者：Collado Gonzalez Mar; Fernandez Espin Vanesa; Montalban Mercedes G; Pamies Ramon; Hernandez Cifre Jose Gines; Diaz Banos F Guillermo; Villora Gloria; Garcia de la Torre Jose

来源：Journal of Nanoparticle Research, 2015, 17(6): 268.

DOI：10.1007/s11051-015-3069-3

• Chitosan
• Gold nanoparticles
• Dynamic light scattering
• Surface plasmon resonance
• Transmission electron microscopy
• Biocompatibility

Chitosan (CS) is a biocompatible polysaccharide with positive charge that is widely used as a coating agent for negatively charged nanoparticles. However, the types of structures that emerge by combining CS and nanoparticles as well as their behaviour are still poorly understood. In this work, we characterize the nanocomposites formed by gold nanoparticles (AuNPs) and CS and study the influence of CS in the expected aggregation process that should experience those nanoparticles under the favourable conditions of low pH and high ionic strength. Thus, at the working CS concentration, we observe the existence of CS structures that quickly trap the AuNPs and avoid the formation of nanoparticle aggregates in environmental conditions that, otherwise, would lead to such an aggregation.

• 出版日期2015-6-13