A novel biosensor for liquid phase determination of glutathione and amoxicillin in biological and pharmaceutical samples using a ZnO/CNTs nanocomposite/catechol derivative modified electrode

作者：Karimi Maleh Hassan^*; Tahernejad Javazmi Fahimeh; Gupta Vinod Kumar; Ahmar Hamid; Asadi Malek Hossein

来源：Journal of Molecular Liquids, 2014, 196: 258-263.

DOI：10.1016/j.molliq.2014.03.049

• Glutathione
• Amoxicillin
• Modified electrode
• Voltammetry

In the present study, the use of a carbon paste electrode modified by 8,9-dihydroxy-7-methyl-12H-benzothiazolo [2,3-b]quinazolin-12-one (DMBQ) and ZnO/CNTs nanocomposite (DMBQ/ZnO/CNTs/CPE) prepared by a simple and rapid method was described. The modified electrode showed an excellent character for electrocatalytic oxidization of glutathione (GSH) and amoxicillin (AMX). Their square wave voltammetric peak current increased linearly with their concentration at the ranges of 0.002-720 and 1.0-950 mu M, respectively with the detection limits of 0.0008 and 0.5 mu M, respectively. The modified electrode was successfully used for the determination of the analytes in real samples with satisfactory results.

• 出版日期2014-8