Protein transport through gold-coated, charged nanopores: Effects of applied voltage

作者：Chun KY; Mafe S^*; Ramirez P; Stroeve P

来源：Chemical Physics Letters, 2006, 418(4-6): 561-564.

DOI：10.1016/j.cplett.2005.11.029

The flux of bovine serum albumin and bovine hemoglobin through charged nanopores inside polymeric membranes is analysed as a function of the applied voltage to the nanopore surface, the solution ionic strength and pH. The electrostatic interaction of the protein with the nanopore surface gives low transport rates except at the protein isoelectric point and the minimum of the effective, voltage-induced nanopore charge. This electrostatic sieving effect allows for the separation of proteins with similar molecular weights.

• 出版日期2006-2-6