Antioxidant and anticancer activities of freshwater green algae, Cladophora glomerata and Microspora floccosa, from Nan River in northern Thailand

作者：Laungsuwon Ratiphan; Chulalaksananukul Warawut^*

来源：Maejo International Journal of Science and Technology, 2013, 7(2): 181-188.

• Cladophora glomerata
• Microspora floccosa
• total phenolic content
• antioxidant activity
• anticancer activity

Organic solvent and hot water extracts of freshwater macroalgae, Cladophora glomerata and Microspora floccosa, harvested from Nan River in northern Thailand were screened for antioxidant and anticancer activities using DPPH free radical scavenging assay and inhibition of proliferation of the KB human oral cancer cell lines respectively. The ethyl acetate extract of C. glomerata showed the highest total phenol content (18.1 +/- 2.3 mg GAE/g), radical scavenging activity (49.8 +/- 2.7% DPPH scavenging at 100 mu g/ml) and in vitro growth inhibition (IC50=1420.0 +/- 66 mu g/g) of the KB cell lines. These results indicate that C. glomerata could be a source of valuable bioactive materials.

• 出版日期2013-8