Assessment of diffusion-weighted imaging for characterizing focal liver lesions

作者：Parsai Arman^*; Zerizer Imene; Roche Oran; Gkoutzios Panos; Miquel Marc E

来源：Clinical Imaging, 2015, 39(2): 278-284.

DOI：10.1016/j.clinimag.2014.09.016

• Diffusion-weighted imaging (DWI)
• Focal liver lesions
• MRI
• Malignant
• Benign

In 150 patients, 153 hepatic lesions (39 metastases, 27 hemangiomas, 26 hepatocellular carcinomas, 25 cysts, 15 adenomas, 8 focal nodular hyperplasias, 5 abscesses, 4 hamartomas, and 4 cholangiocarcinomas) were evaluated during a 24-month period. Apparent diffusion coefficient (ADC) values of benign lesions (1.994x10(-3)mm(2) s(-1)) were significantly higher than ADC values of malignant lesions (1.070x10(-3)mm(2) s(-1)). Mean ADC value for solid benign lesions (1.143x10(-3)mm(2) s(-1) +/- 0.214x10(-3)mm(2) s(-1)) was not significantly different from malignant lesions. ADC values did not allow differentiating malignant from benign solid lesions (area under the curve=0.61). ADC cutoff value threshold of 1.6x10(-3)mm(2) s(-1) yielded higher accuracy for differentiating benign from malignant lesions.

• 出版日期2015-4