SMY2 and SYH1 suppress defects in ribosome biogenesis caused by ebp2 mutations

作者：Okano Akira; Wan Kun; Kanda Kazuhiro; Yabuki Yukari; Funato Kouichi; Mizuta Keiko^*

来源：Bioscience Biotechnology and Biochemistry, 2015, 79(9): 1481-1483.

DOI：10.1080/09168451.2015.1031077

• ribosome biogenesis
• EBP2
• SMY2
• SYH1

Ebp2 is an assembly factor of the 60S ribosomal subunit in yeast. We demonstrate that overexpression of SMY2 or SYH1 partially suppresses defects in growth and ribosome biogenesis of ebp2 mutants, and that smy2 and syh1 exhibit synthetic growth defects with the ebp2 allele. These results suggest that Smy2 and Syh1 may be involved in ribosome biogenesis in relation to Ebp2.

• 出版日期2015-9-2